Gut enzymes could make universal organ donation a reality

The human body it’s a bit like a constellation, isn’t it? All our parts come together to form a recognizable and empathetic thing. Reverse Daily readers know their constellations well, and many of you answered last week’s question praising Orion, the Pleiades, Cassiopeia, and the Big Dipper.

Selena V. always felt like the hunter Orion was watching over her, and after leaving town and finally getting to see the stars, Henry C. made sure to point the iconic three-star belt of the constellations at her daughter when she was growing up. Patrick F. is a big fan of the Big Dipper, which is “basically the only [he] can identify themselves without a star application” (idem!). Read more about the body and the stars in today’s news Reverse Daily. We hope today brings you clear skies.

This is an adapted version of Reverse Daily newsletter of Tuesday, February 22, 2022. Subscribe for free and earn rewards for daily reading in your inbox. ✉️

Enzymes could change everything.CHOKSAWATDIKORN/SCIENCE PHOTO LIBRARY/Science Photo Library/Getty Images

Human organs are so high maintenance – they need regular checks and care, but even if you provide it, they might decide to get lazy and stop working properly. If this happens, they are difficult to replace. “One of the major factors preventing recipients from receiving available organs is blood type,” writes Reverse health writer Katie MacBride.

A new study in Science Translational Medicine aims to circumvent this problem by making all organs compatible at all levels; it only requires a few intestinal enzymes.

In 2018, researchers discovered a group of enzymes produced by gut bacteria. Two of these enzymes, when combined, were able to remove sugars from the A and B antigens on red blood cells and turn them into what are essentially O blood cells. With this in mind, the researchers turned to the system Ex Vivo Lung Perfusion (EVLP), about which a researcher tells Reverse is an “intensive care unit for the lungs”; he keeps a pair of donor lungs until they are safe in a new body.

The researchers hypothesized that if they ran the gut enzymes they discovered through EVLP, it could “”scrub”” antigens from the lungs of a blood type A donor and turn them into lungs. that could theoretically go to a recipient of any blood type,” writes MacBride. So far, the study results seem to support their hypothesis.

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What your gut is telling you: The gut could be the human ‘first brain’

A stem cell here or there could cure you.Little Hand Images/Moment/Getty Images

“The line between man and machine is eroding,” writes editor Jennifer Walter, “We have humanoid robots that express emotions, ‘living’ robots that self-replicate, and implants that enable people to control prostheses with their minds.” It might thrill your senses of uniqueness, but rest assured that many of these bots are designed with you in mind.

Take the brainless artificial fish, for example, which scientists constructed from plastic, gelatin and human stem cells like gods in an aquatic prologue. Walter writes that the fish is “a step up from the old hybrid robots that this team has created before from artificial cells and materials”, easily mimicking the actual movement of the fish “thanks to the living cells that make up its muscle layers. “.

Alright, alright, I know it’s terrifying. Do you think I like knowing that there’s a biohybrid fish wandering mindlessly through some scientist’s aquarium somewhere? I don’t have one, he doesn’t have eyeballs. But it’s for a good cause – Walter notes that the fish’s flops are very similar to the way the human heart pumps, making this an important first step towards a working artificial heart. “Since anyone’s stem cells could theoretically be used to grow heart muscle,” writes Walter, the researchers believe that this gummy fish “could open the door to a personalized approach to growing artificial hearts.”

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Pretend until you make it: Why Scientists Use Fish Psychopathy Tests

Attention: spheres in front.Mark Stevenson/Stocktrek Images/Stocktrek Images/Getty Images

Aliens may be the universe’s best-kept secret, but that won’t stop scientists from looking for them in even the most hypothetical hiding places. Case in point: a team of researchers recently decided to estimate how many Dyson spheres (a theoretical megastructure that sucks energy from stars) envelop our Milky Way.

“Using optical data from the Gaia Observatory, a space telescope launched by the European Space Agency in 2013, and infrared data from the AllWISE program – which provides the most comprehensive view of the sky in full mid-infrared – the The researchers behind the new study analyzed 260,000 stars in the Milky Way,” writes Passant Rabie. “After gathering the luminosity of these stars, the team then created Dyson Sphere models that showed their potential temperature […] and what part of the star they would cover.

The researchers compared their Dyson Sphere models to records of the stars’ actual brightness and temperature, ultimately determining that only a paltry sum of stars makes a good Dyson Sphere match. But it’s better than nothing, right?

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Do you have a mega-mind? : James Cameron ripped off ‘Alien’ before making ‘Aliens’

You can’t bleach that.Matt Mawson/Unreleased Moment/Getty Images

Fossil fuel giants like ExxonMobil and BP want you on their side, which is why they often publicly outline “a transition to a green future amid a looming climate crisis,” writes Tara Yarlagadda. “But new research suggests that […] they quietly maintain oil and gas production and do not invest significantly in renewable energy.

This research was published in PLOS ONE Wednesday, and it indicates that Chevron, ExxonMobil, BP and Shell look more like little green monsters than rosy-cheeked innocents, making surprisingly little effort between the years 2009 and 2020 to transition to clean energy. For example, “ExxonMobil [generated] no electricity from clean energy sources – such as wind and solar – over the period studied.

The study’s authors found this by analyzing “specific keywords relating to climate and clean energy in company annual reports” and comparing them to public promises, “assigning scores based on the how corporate operations have moved away from fossil fuels,” Yarlagadda writes. The facts show that they did not.

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The money where your mouth is: Sea spray could spray you with toxic chemicals

Galileo was right!Photo 12/Universal Pictures Group/Getty Images

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  • On this day in history: Italian astronomer Galileo published the book A dialogue on the two main world systems that day in 1632. Unfortunately for Galileo, who correctly believed that the planets orbit the sun, the publication led to censorship and house arrest (although he was convicted of death at many times).
  • Song of the day: “House Arrest Tingz”, by NBA YoungBoy.


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